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Takuji Yamaguchi Selected Research

Yi-Gan San

5/2015Yokukansan, a traditional Japanese medicine, decreases head-twitch behaviors and serotonin 2A receptors in the prefrontal cortex of isolation-stressed mice.
1/2014Yokukansan, a traditional Japanese medicine, adjusts glutamate signaling in cultured keratinocytes.
12/2012Ameliorative effect of yokukansan on vacuous chewing movement in haloperidol-induced rat tardive dyskinesia model and involvement of glutamatergic system.
11/2011Ameliorating effect of Yokukansan on the development of atopic dermatitis-like lesions and scratching behavior in socially isolated NC/Nga mice.
4/2011Effects of yokukansan and donepezil on learning disturbance and aggressiveness induced by intracerebroventricular injection of amyloid β protein in mice.
10/2010Electron-microscopic examination of effects of yokukansan, a traditional Japanese medicine, on degeneration of cerebral cells in thiamine-deficient rats.
10/2009Effects of yokukansan, a traditional Japanese medicine, on memory disturbance and behavioral and psychological symptoms of dementia in thiamine-deficient rats.
10/2009Oral administration of Yokukansan inhibits the development of atopic dermatitis-like lesions in isolated NC/Nga mice.
9/2009Effect of yokukansan, a traditional Japanese medicine, on social and aggressive behaviour of para-chloroamphetamine-injected rats.
2/2009Ameliorative effects of yokukansan, a traditional Japanese medicine, on learning and non-cognitive disturbances in the Tg2576 mouse model of Alzheimer's disease.

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Takuji Yamaguchi Research Topics

Disease

4Atopic Dermatitis (Atopic Eczema)
09/2017 - 10/2009
4Sleep Initiation and Maintenance Disorders (Insomnia)
11/2011 - 07/2004
3Dementia (Dementias)
05/2015 - 10/2009
2Adenocarcinoma
08/2019 - 01/2012
2Inflammation (Inflammations)
09/2017 - 02/2017
2Dermatitis
02/2017 - 01/2014
2Learning Disabilities (Learning Disability)
04/2011 - 10/2010
2Alzheimer Disease (Alzheimer's Disease)
06/2009 - 02/2009
2Hypoxia (Hypoxemia)
03/2007 - 07/2004
1Acne Vulgaris
02/2017
1Hallucinations (Hallucination)
05/2015
1Mood Disorders (Mood Disorder)
04/2014
1Tardive Dyskinesia
12/2012
1Cachexia
01/2012
1Carcinoma (Carcinomatosis)
01/2012
1Neoplasms (Cancer)
01/2012
1Thiamine Deficiency
10/2010
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2004
1Neurasthenia
07/2004
1Tremor (Tremors)
07/2004
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
07/2004
1Amnesia (Dissociative Amnesia)
07/2004

Drug/Important Bio-Agent (IBA)

10Yi-Gan SanIBA
05/2015 - 02/2009
2Proteins (Proteins, Gene)FDA Link
04/2011 - 06/2009
2Potassium CyanideIBA
03/2007 - 07/2004
2Cholinergic Agents (Cholinergics)IBA
03/2007 - 07/2004
2Scopolamine (Hyoscine)FDA Link
03/2007 - 07/2004
1Biomarkers (Surrogate Marker)IBA
08/2019
1Interleukin-33IBA
09/2017
1InterferonsIBA
09/2017
1HydrogenIBA
09/2017
1Gallic AcidIBA
02/2017
1peoniflorinIBA
02/2017
1prunasinIBA
02/2017
1keishibukuryoganIBA
02/2017
1yokuininIBA
02/2017
1Reactive Oxygen Species (Oxygen Radicals)IBA
02/2017
1Oxygen (Dioxygen)IBA
02/2017
1azelaic acid (Azelex)FDA Link
02/2017
15-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
05/2015
1Hallucinogens (Psychedelics)IBA
05/2015
1Pharmaceutical PreparationsIBA
05/2015
1koso-sanIBA
04/2014
1Antidepressive Agents (Antidepressants)IBA
04/2014
1Glutamine (L-Glutamine)FDA Link
01/2014
1Glutamate Receptors (Glutamate Receptor)IBA
01/2014
1Glutamic Acid (Glutamate)FDA Link
01/2014
1Haloperidol (Haldol)FDA LinkGeneric
12/2012
1haloperidol decanoateFDA LinkGeneric
12/2012
1bu-zhong-yi-qi-tangIBA
01/2012
1Therapeutic UsesIBA
01/2012
1Triglycerides (Triacylglycerol)IBA
01/2012
1CytokinesIBA
01/2012
1Interleukin-6 (Interleukin 6)IBA
01/2012
1Amyloid (Amyloid Fibrils)IBA
04/2011
1Donepezil (Aricept)FDA LinkGeneric
04/2011
1Thiamine (Aneurin)FDA Link
10/2009
1Amyloid beta-PeptidesIBA
06/2009
13,6'-disinapoylsucroseIBA
03/2007
1Choline O-Acetyltransferase (Choline Acetyltransferase)IBA
03/2007
1sinapinic acidIBA
03/2007
1Acetylcholine (Acetylcholine Chloride)FDA Link
03/2007
1pazufloxacinIBA
10/2004
1Doxorubicin (Adriamycin)FDA LinkGeneric
10/2004
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
10/2004
1OxotremorineIBA
07/2004

Therapy/Procedure

2Kampo Medicine (Kampo)
05/2015 - 01/2012
1Oral Administration
10/2009
1Decompression
03/2007
1Ligation
03/2007
1Chinese Traditional Medicine (Traditional Chinese Medicine)
07/2004